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When the glycolysis rate is less, 2,3 BPG production is less, which is a by-product of glycolysis

While these methods exist, individual calculations are not the norm, and for an eligible clinician in only one APM Entity our current policy does not provide for an individual determination

Ethics declarations Ethics statement and informed consent All procedures followed were in accordance with the ethical standards of the responsible committee on human experimentation (institutional) and with the Helsinki Declaration of 1975, as revised in 2000

Boys, however, have only one copy of the gene, which they inherit from the mother

Not all patients experience these side effects, but in those who do, both will go away shortly

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